Automated Process Design

- Responsible for the overall management of the department and all major decisions regarding the selection, maintenance and repair of equipment and systems in the facility. - Establishes the strategies for the biopharmaceuticals manufacturing plant to achieve desired efficiency levels from equipment and systems and drives cross-functional collaborations and continuous improvements efforts. - Accountable for meeting the department's operational and financial targets. - Champions innovation of equipment and systems within the facility and drives TC SMR applications of analytics, technology and automation to enhance the maintenance and management of equipment, systems and energy resources. - Retains accountability for risks and regulatory compliance for the department and approves contingency plans in the event of disruptions and emergencies. - Inspiring and influential leader, highly skilled in developing capabilities, building strong teams and engaging internal and external stakeholders to drive organisational success. - Have a passion for driving a culture of innovation within and beyond the department to enhance the overall reliability and efficiency of biopharmaceuticals manufacturing operations.

- Applies engineering principles and techniques to optimise the equipment and systems within the manufacturing facility. - Provides technical guidance and direction for the installation of equipment and systems. - He develops plans for the maintenance of equipment and systems, and recommends engineering solutions to troubleshoot faults. - Innovates equipment and systems, and contributes to manufacturing equipment and systems improvement projects by conducting feasibility assessments and tests on TC SMR technologies. - Manage energy resources and utilities by developing solutions to optimise machine availability and energy efficiency. - Ensure compliance with Standard Operating Procedures (SOPs), Health, Safety and Environment (HSE) regulations and Current Good Manufacturing Practices (CGMPs) within his purview. - Develops guidelines and conducts equipment qualification and validation in line with biopharmaceuticals manufacturing regulatory requirements. - Possess an enquiring and analytical mind and have a knack for investigating issues, analysing multifaceted engineering problems and developing solutions. - A strong team player who can guide and mentor others, and communicate technical advices and solutions to colleagues beyond the team.

The Engineering and Maintenance Manager is responsible for managing and deploying resources to install, maintain and repair equipment and systems in the facility in line with organisational objectives. He/She translates the organisational strategies into tactical plans for the department and facilitates cross-functional collaborations and continuous improvements efforts. He manages resources to ensure that utilities and systems are adequate to support the achievement of organisational targets. He also develops plans to validate equipment and manage risks within the department. In addition, he is responsible for cascading key objectives to teams and individuals and managing team and project budgets. As a people manager, the Engineering and Maintenance Manager oversees manpower, financial, training and resource planning deployment within the Engineering and Maintenance department. The Engineering and Maintenance Manager is expected to serve as a role model in operational excellence in the department, and should be a personable and inspiring leader who can communicate well and influence internal and external stakeholders. He should also have a strategic, analytical mind to resolve problems and make effective decisions for the department when faced with complex situations.

The Engineering and Maintenance Principal/Senior Engineer applies advanced engineering principles and techniques to troubleshoot complex engineering problems encountered within the manufacturing facility and provides expert technical advice to guide the installation and maintenance of equipment and systems. He/She is expected to lead the technical cross-collaboration with the Process Development/Manufacturing Science and Technology (PD/MSAT) department in order to identify appropriate biopharmaceuticals manufacturing equipment and optimise their functionalities. The Engineering and Maintenance Principal/Senior Engineer leads manufacturing equipment and systems innovation projects by guiding feasibility assessments and tests on TC SMR technologies. He is expected to review and approve solutions and initiatives to optimise machine availability while managing energy and utility use. He sets parameters for equipment qualification and validation in line with biopharmaceuticals manufacturing regulatory requirements. The Principal/Engineer must ensure compliance with Standard Operating Procedures (SOPs), Health, Safety and Environment (HSE) regulations and Current Good Manufacturing Practices (CGMPs) within his purview. The Engineering and Maintenance Principal/Engineer carries the responsibility of the in-house technical expert. He should possess a deep passion for analysing and resolving multifaceted engineering problems and be able to apply advanced critical and analytical thinking skills to deal with immediate situations. He should have a developmental and amiable approach in his interactions working as part of a team while guiding and mentoring others. He must also be able to communicate engineering concepts in a manner that will be understood by others within and beyond the team.

The Process Development/MS&T Director approves and guides the development of TC SMR or improved processes in the biopharmaceuticals manufacturing facilities and leads subsequent change management initiatives. He/She endorses all major decisions regarding piloting TC SMR technology, implementing process scale-up as well as monitoring and optimising existing processes. In addition, he is accountable for the Process Development/MS&T department meeting its operational and financial targets. The Process Development/MS&T Director holds ultimate responsibility for the development, monitoring and improvement of biopharmaceuticals manufacturing processes within the facilities. The Process Development/MS&T Director is required to maintain a broad, strategic perspective, applying transdisciplinary thinking and a global mindset, to consider issues within the wider context and make effective decisions that will impact the biopharmaceuticals manufacturing facilities. He should be passionate in driving a culture of innovation within and beyond the department to enhance the overall reliability and efficiency of biopharmaceutical manufacturing facilities. He is a strong leader who applies his interpersonal skills to engage with internal and external stakeholders to drive the department's activities.

The Process Development/MS&T Manager reviews the operational and financial viability of developing, monitoring and improving biopharmaceuticals manufacturing processes within the facilities. He/She translates the departments objectives and priorities into actionable operating plans and Key Performance Indicators (KPIs) for Process Development/MS&T teams and tracks the progress. He is responsible for optimising internal processes while keeping in line with external guidelines and managing risks for the department. The Process Development/MS&T Manager is responsible for facilitating cross-departmental collaboration in order to successfully implement large-scale manufacturing processes for TC SMR biopharmaceuticals products or significant changes to equipment, systems and processes for existing products. The Process Development/MS&T Manager is expected to serve as a role model in the department and should be a personable and inspiring leader who can communicate well to influence internal and external stakeholders. He should be a champion for innovation and particularly enjoys leading efficiency and improvement initiatives across the organisation.